NAD+ is a critical coenzyme present in all living cells. While not a peptide, it is a cornerstone compound in longevity research and is commonly available through research peptide suppliers. Its role in cellular energy production, DNA repair, and epigenetic regulation places it at the center of aging biology.
Research Applications
Aging and longevity research, sirtuin biology, mitochondrial function, DNA repair, neurodegenerative disease models, and metabolic health.
Dosage Information (Research Use)
Research administration routes: subcutaneous, intramuscular, and intravenous at various concentrations. Oral precursors (NMN, NR) also widely studied. Research use only.
Reconstitution & Handling
Dissolve in sterile water or bacteriostatic water. NAD+ is sensitive to light and heat — prepare fresh and use promptly.
Half-Life & Pharmacokinetics
Plasma half-life is short, but cellular NAD+ pool restoration has prolonged metabolic effects.
Reported Observations in Literature
IV administration: flushing, nausea, cramping (generally transient). Subcutaneous: injection site discomfort. Oral precursors generally well-tolerated.
Key Research References
- Yoshino J, et al. “NAD+ intermediates: The biology and therapeutic potential of NMN and NR.” Cell Metab. 2018