Longevity ⏱ Half-life: Short. Experimental

Pancragen

Pancragen (KEDW Peptide)

Updated March 15, 2026

Evidence at a Glance

Regulatory statusExperimental
Khavinson tetrapeptide (Lys-Glu-Asp-Trp) bioregulator; Russian-language animal/cell data, no approvals
Human evidenceNone
Animal evidenceLimited

A short peptide bioregulator from the Khavinson program studied in Russian animal and cell work for pancreatic and metabolic gene-expression effects, with no controlled human trials.

What the research does not support

  • It is not a proven treatment for diabetes or metabolic disease in humans.
  • No randomized controlled human trials support its use.
  • It is not an approved drug in Western regulatory systems.
Half-Life
Short.
Mol. Weight
~562 g/mol

What is Pancragen?

Pancragen is a synthetic peptide bioregulator designed to support pancreatic tissue function and metabolic regulation.

Research Applications

Pancreatic beta cell support, glucose metabolism, diabetes prevention research, and metabolic aging.

Dosage Information (Research Use)

10-20 mg/day for 10-30 day courses. Research use only.

Reconstitution & Handling

Standard.

Half-Life & Pharmacokinetics

Short.

Reported Observations in Literature

Generally well-tolerated.

Key Research References

  • Khavinson VK. “Peptide Bioregulators.” 2003

How Pancragen Works

Pancragen modulates gene expression in pancreatic cells, supporting insulin-producing beta cell resilience and glucose homeostasis.

Research Findings

Studied in metabolic research for pancreatic function support and diabetes prevention models.

Dosage & Administration

10-20 mg/day for 10-30 day courses. Research use only.

Safety & Side Effects

Generally well-tolerated.

Important: All safety information is derived from published research, primarily animal studies. No controlled human clinical trial data exists unless explicitly noted. This compound is sold for research purposes only.

Quick Facts

Sequence Lys-Glu-Asp-Trp
Molecular Weight ~562 g/mol
Half-Life Short.
Available Sizes 5mg
Storage Lyophilized: -20°C.

Key Research References

  • Khavinson VK. "Peptide Bioregulators." 2003

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