FGL is a peptide mimetic of neural cell adhesion molecule (NCAM) that activates fibroblast growth factor receptor signaling to promote synaptic plasticity and memory formation. It represents a targeted approach to enhancing the brain’s natural cell adhesion-mediated learning processes.
Research Applications
Memory enhancement, synaptic plasticity (LTP), age-related cognitive decline models, neuroprotection, and NCAM/FGFR signaling research.
Dosage Information (Research Use)
Animal research: 5-10 mg/kg subcutaneously or IV. Human dosing not established. Research use only.
Reconstitution & Handling
Standard BAC water reconstitution.
Half-Life & Pharmacokinetics
Not fully characterized in published data.
Reported Observations in Literature
Limited data. Generally well-tolerated in animal models.
Key Research References
- Bhatt DK, et al. “FGL, a neural cell adhesion molecule-derived peptide, is neuroprotective.” Ann Neurol. 2005