Follistatin-344 is a naturally occurring glycoprotein that acts as a powerful antagonist of myostatin — the body’s primary muscle growth limiter. By binding and neutralizing myostatin, follistatin removes the molecular brake on skeletal muscle development.
Research Applications
Myostatin inhibition, muscle hypertrophy research, muscular dystrophy models, and body composition studies.
Dosage Information (Research Use)
Research protocols: 100-300 mcg/day subcutaneously for 10-30 day cycles. Research use only.
Reconstitution & Handling
Reconstitute carefully with BAC water — larger protein requires gentle handling. Do not shake.
Half-Life & Pharmacokinetics
Relatively short, but downstream effects on muscle signaling persist for days.
Reported Observations in Literature
Limited human data. Theoretical concerns about effects on reproductive hormones (activin is involved in FSH regulation).
Key Research References
- Haidet AM, et al. “Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors.” Proc Natl Acad Sci. 2008