Selank is a synthetic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It combines anxiolytic (anti-anxiety) properties with cognitive enhancement and immunomodulation — a unique combination not found in traditional pharmaceutical approaches.
Research Applications
Anxiety research (without sedation), cognitive enhancement under stress, memory and learning studies, immunomodulation, and BDNF expression research.
Dosage Information (Research Use)
Research protocols: 200-600 mcg/day, subcutaneous or intranasal. Duration typically 14-30 days in published studies. Research use only.
Reconstitution & Handling
Standard BAC water reconstitution for subcutaneous use. Can also be prepared in saline for intranasal research.
Half-Life & Pharmacokinetics
Several minutes in plasma, but functional CNS effects persist for hours, suggesting tissue-level accumulation or downstream signaling cascades.
Reported Observations in Literature
Remarkably clean safety profile in published data: no sedation, no cognitive impairment, no addiction or tolerance, no withdrawal. Mild nasal irritation with intranasal route.
Key Research References
- Semenova TP, et al. “Selank has an effect on the expression of genes encoding neurotrophic factors.” Bull Exp Biol Med. 2010
- Zozulya AA, et al. “The inhibitory effect of Selank on enkephalin-degrading enzymes.” Bull Exp Biol Med. 2001