Adipotide takes a radically different approach to fat reduction — rather than modifying metabolism or appetite, it directly targets and destroys the blood vessels that supply white adipose tissue, causing fat cell death through ischemia.
Research Applications
Targeted fat tissue ablation, obesity research, vascular targeting studies, and prohibitin biology.
Dosage Information (Research Use)
Primate research: 0.5-1 mg/kg subcutaneously. Human safety not established. Research use only.
Reconstitution & Handling
Standard BAC water reconstitution.
Half-Life & Pharmacokinetics
Not well characterized in published pharmacokinetic data.
Reported Observations in Literature
Renal toxicity reported in primate studies (kidney is highly vascularized). Dehydration effects noted. Not considered safe for human use.
Key Research References
- Barnhart KF, et al. “A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.” Sci Transl Med. 2011